与原发性IgA肾病患者肾间质纤维化程度相关的因素分析
Shandong Medical Journal(2019)
Abstract
目的 分析与原发性IgA肾病(IgAN)患者肾间质纤维化(RIF)程度相关的因素.方法 102例原发性IgAN患者根据RIF程度不同分为1级70例、2级16例、3级7例,采用单因素分析法比较各级患者的临床资料,多元线性回归分析法分析IgAN患者肾脏RIF程度的相关因素.结果 单因素分析显示,各级患者平均动脉压、24 h尿蛋白定量、血红蛋白、血磷、血肌酐(Scr)、尿素氮、尿酸、估算肾小球滤过率、人附睾蛋白4(HE4)比较有差异(P均<0.05).多因素分析显示,Scr水平、HE4表达量在一定程度上可反映RIF的严重程度.结论 IgAN患者肾脏RIF程度的相关因素是Scr水平及HE4表达量.
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