益赛普联合塞来昔布治疗强直性脊柱炎的临床疗效观察
Chinese Journal of Clinical Rational Drug Use（2018）
Abstract
目的 观察益赛普联合塞来昔布治疗强直性脊柱炎的临床疗效.方法 选取收治的强直性脊柱炎患者70例,随机分为观察组和对照组,每组35例.对照组应用柳氮磺胺吡啶联合塞来昔布治疗,观察组应用益赛普联合塞来昔布治疗.观察比较2组患者治疗后实验室指标(红细胞沉降率、C反应蛋白水平)变化、治疗效果及不良反应发生情况.结果 治疗后2组红细胞沉降率、C反应蛋白水平指标均得以改善,观察组改善程度较对照组更为明显(P＜0.05);观察组患者治疗总有效率为94.29％,高于对照组的74.29％ (P ＜0.05);观察组不良反应发生率为5.71％,低于对照组的22.86％ (P ＜0.05).结论 益赛普与塞来昔布联合治疗强直性脊柱炎,有助于快速改善患者临床症状,治疗有效率较高,且不良反应发生率低,值得临床推广应用.
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