卡泊三醇软膏联合窄谱UVB治疗寻常型银屑病的临床疗效分析
Chinese Journal of Modern Drug Application（2018）
Abstract
目的 探讨卡泊三醇软膏联合窄谱中波紫外线(UVB)治疗寻常型银屑病的临床疗效.方法 80例寻常型银屑病患者,采用自身对照法,以患者的正中线为界限,左侧皮损单用窄谱UVB治疗,右侧皮损采用卡泊三醇软膏与窄谱UVB联合治疗,比较两种治疗方法的临床疗效并观察不良反应情况.结果 卡泊三醇软膏与窄谱UVB联合治疗无效3例,有效3例,显效44例,痊愈30例,总有效率为96.25％(77/80);窄谱UVB治疗无效14例,有效8例,显效36例,痊愈22例,总有效率为82.50％(66/80);两组总有效率比较差异具有统计学意义(P<0.05).2例患者出现轻度恶心、头晕,5例患者辐照部位出现红斑,7例患者存在明显皮肤瘙痒、干燥感.所有患者均未出现中断治疗.结论 采用卡泊三醇软膏与窄谱UVB联合治疗寻常型银血病,临床疗效显著,安全性高,具有重要的临床价值.
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