生长抑素泵入法联合持续血液净化治疗急性重症胰腺炎的疗效观察及安全性分析

Chinese Journal of Integrated Traditional and Western Medicine on Digestion（2016）

Cited 16|Views4

Abstract

[目的]探究与分析生长抑素泵入法联合持续血液净化治疗急性重症胰腺炎的疗效及安全性.[方法]选取我院自2014年5月～2015年5月收治的120例急性重症胰腺炎,采取随机数字表法分为常规治疗组与联合治疗组,每组各60例,常规治疗组给予生长抑素泵入法治疗,联合治疗组在其基础上联合持续血液净化治疗,对比两者治疗前、治疗后24 h、72 h的MAP、HR、PCT、CRP水平、慢性健康状况评分及不良反应.[结果]常规治疗组与联合治疗组治疗后24 h的MAP、HR、PCT、CRP水平与治疗前比较差异有统计学意义(P＜0.05).常规治疗组与联合治疗组治疗后72 h的MAP、HR、PCT、CRP水平与治疗前、治疗后24 h比较差异有统计学意义(P＜0.05).常规治疗组治疗后24 h、治疗后72 h的的MAP、HR、PCT、CRP水平与联合治疗组治疗后24 h、治疗后72 h比较差异有统计学意义(P＜0.05).常规治疗组与联合治疗组治疗后24 h、治疗后72 h的APACHEⅡ评分较治疗前比较差异均有统计学意义(P＜0.05).常规治疗组治疗后24 h、治疗后72 h的APACHEⅡ评分较联合治疗组治疗后24 h、治疗后72h比较差异有统计学意义(P＜0.05).[结论]在生长抑素泵入法基础上联合持续血液净化治疗急性重症胰腺炎的疗效显著,可有效降低血清PCT及CRP水平,改善患者生活质量,安全性较高,值得推广与应用.

Key words

somatostatin,continuous blood purification,severe acute pancreatitis,curative effect,security

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Pretraining has recently greatly promoted the development of natural language processing (NLP)
We show that M6 outperforms the baselines in multimodal downstream tasks, and the large M6 with 10 parameters can reach a better performance
We propose a method called M6 that is able to process information of multiple modalities and perform both single-modal and cross-modal understanding and generation
The model is scaled to large model with 10 billion parameters with sophisticated deployment, and the 10 -parameter M6-large is the largest pretrained model in Chinese
Experimental results show that our proposed M6 outperforms the baseline in a number of downstream tasks concerning both single modality and multiple modalities We will continue the pretraining of extremely large models by increasing data to explore the limit of its performance

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