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    • DWI多参数模型在FIGO 2018宫颈癌新分期的应用价值

    Yu ZHANG,Chuan-hai JIA,Qing-guo DING,Wen-bin SHEN,Hong-qiang ZHANG,Li-na HUANG

    Journal of China Clinic Medical Imaging（2020）

    Cited 1|Views7
    Abstract
    目的:探讨DWI多指数模型定量参数在FIGO 2018宫颈癌新分期中的应用价值.方法:回顾性分析51例经手术病理证实且术前未经任何治疗的宫颈癌患者MR-DWI指数模型定量参数.所有患者均行MR常规序列和DWI序列扫描;由两位放射科诊断医生(间隔2周重复测量)根据2018 FIGO分期测量早期官颈癌与晚期宫颈癌的DWI单指数、双指数及拉伸指数模型所有参数值(测量参数包括ADCstand、D、D*,f、DDC、α),并进行组间比较,采用受试者工作特征(ROC)曲线下面积评价各参数的诊断效能及最佳诊断阈值.结果:同一测量者前后两次测量各参数值组内相关系数结果表明ADCstand、D、f、DDC及α值的一致性均较好,D*值一致性中等.早期官颈癌组ADCstand、D、DDC值低于晚期宫颈癌组,组间比较有统计学差异(P,＜0.05),D*、f及α值组间比较无统计学差异;早期组中Ⅰ B1期、Ⅰ B2期与晚期组中的Ⅰ B3期各参数值进行比较.ADCstand、D、DDC值具有统计学差异(P＜0.05),D*、f及α值无统计学差异.定量参数D及ADCstand具有较高诊断效能,曲线下面积(AUC)分别为0.957、0.904,诊断阈值为0.87×10-3 mm2/s、1.19×10-3 mm2/s.结论:根据FIGO 2018宫颈癌新分期系统,DWI多指数模型有助于区分早期官颈癌与晚期宫颈癌,其中参数D和ADCstand具有较高的诊断效能,在宫颈癌分期及精准诊疗中具有一定参考价值.
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    【要点】：本研究探讨了DWI多指数模型定量参数在2018 FIGO宫颈癌分期中的应用价值，发现参数D和ADCstand对区分早期与晚期宫颈癌具有较高的诊断效能。
    

    【方法】：通过回顾性分析51例经手术病理证实且术前未经治疗的宫颈癌患者的MR-DWI指数模型定量参数，比较早期官颈癌与晚期宫颈癌的DWI单指数、双指数及拉伸指数模型参数值。
    

    【实验】：由两位放射科诊断医生对患者的DWI参数进行测量，使用的数据集为51例宫颈癌患者的数据，结果表明ADCstand、D、DDC值在早期官颈癌与晚期宫颈癌组间存在统计学差异，而D*、f及α值无统计学差异，定量参数D及ADCstand的ROC曲线下面积分别为0.957和0.904。