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无痛肠镜安全性的临床研究(附1700例报告)

China Journal of Endoscopy(2011)

Cited 10|Views14
Abstract
目的 探讨丙泊酚复合小剂量芬太尼和咪唑安定应用于无痛肠镜检查的安全性.方法 将1 700例受检者依据自愿性分为无痛肠镜组(A组,n =839)和常规肠镜组(B组,n=861);A组从静脉依次缓慢注入咪唑安定0.01 mg/kg、芬太尼0.001 mg/kg和丙泊酚1~1.5 mg/kg,睫毛反射反应迟钝即可置入肠镜检查;B组按常规方法进行肠镜检查;专人评估受检者的术中和术后恢复情况及不良反应.结果 A、B两组术中和术后的HR、BP及SPO2差异无显著性(P>0.05),不良反应发生率A组显著低于B组(P<0.05),且肠镜检查成功率A组高于B组(P<0.05),用时A组明显短于B组(P<0.05).结论 丙泊酚复合小剂量芬太尼和咪唑安定实施无痛肠镜检查是安全可行的.未出现肠穿孔、心博和呼吸明显抑制乃至骤停等严重并发症.
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