静息态脑功能成像评价夜磨牙者的大脑默认网络
Chinese Journal of Tissue Engineering Research（2021）
Abstract
背景:夜磨牙是常见的一种口腔副功能,但是其病因现在尚不明确.通过很多对夜磨牙患者进行心理调查问卷发现,夜磨牙与心理因素有关,但是二者之间的具体联系与机制并不清晰.目的:分析夜磨牙患者大脑默认网络的改变,探讨夜磨牙患者静息态脑网络状态.方法:自2018年11月至2019年5月对20名经多导睡眠监测确诊的夜磨牙患者(夜磨牙组)及20名年龄、性别、受教育年限相匹配的无症状志愿者(对照组),在夜间20:00至23:00点采用3.0T核磁共振扫描仪行静息态脑功能磁共振成像检查,采用独立成分分析方法分离静息态脑网络,提取默认网络的成分进行统计学分析,首先使用单样本t检验制作网络成分模板,然后使用双样本t检验进行默认网络成分的比较.结果 与结论:夜磨牙组楔前叶默认网络内功能连接较对照组减弱,差异有显著性意义(t=-3.319,P＜0.05),提示夜磨牙患者大脑静息态时默认网络存在异常.
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