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Signaling Through FcγRIIA and the C5a-C5aR Pathway Mediates Platelet Hyperactivation in COVID-19

Sokratis A. Apostolidis,Amrita Sarkar,Heather M. Giannini,Rishi R. Goel,Divij Mathew,Aae Suzuki,Amy E. Baxter,Allison R. Greenplate,Cecile Alanio,Mohamed Abdel-Hakeem,Derek A. Oldridge,Josephine R. Giles,Jennifer E. Wu,Zeyu Chen,Yinghui Jane Huang,Jonathan Belman,Ajinkya Pattekar,Sasikanth Manne,Oliva Kuthuru,Jeanette Dougherty,Brittany Weiderhold,Ariel R. Weisman,Caroline A. G. Ittner,Sigrid Gouma,Debora Dunbar,Ian Frank,Alexander C. Huang,Laura A. Vella,John P. Reilly,Scott E. Hensley,Lubica Rauova, Liang Zhao,Nuala J. Meyer,Mortimer Poncz,Charles S. Abrams,E. John Wherry

Frontiers in Immunology（2022）

Cited 31|Views16
Key words
platelet,COVID-19,Fc gamma RIIa,complement,fostamatinib
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