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Structure of PDE3A-SLFN12 Complex Reveals Requirements for Activation of SLFN12 RNase

Colin W. Garvie,Xiaoyun Wu,Malvina Papanastasiou,Sooncheol Lee,James Fuller,Gavin R. Schnitzler, Steven W. Horner,Andrew Baker,Terry Zhang,James P. Mullahoo,Lindsay Westlake,Stephanie H. Hoyt,Marcus Toetzl,Matthew J. Ranaghan,Luc de Waal,Joseph McGaunn,Bethany Kaplan,Federica Piccioni,Xiaoping Yang,Martin Lange,Adrian Tersteegen,Donald Raymond,Timothy A. Lewis,Steven A. Carr,Andrew D. Cherniack,Christopher T. Lemke,Matthew Meyerson,Heidi Greulich

Nature Communications（2021）

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Cancer therapy,Cell death,Cryoelectron microscopy,Structural biology,X-ray crystallography,Science,Humanities and Social Sciences,multidisciplinary
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