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Bioanalytical Challenges Due to Prior Checkpoint Inhibitor Exposure: Interference and Mitigation in Drug Concentration and Immunogenicity Assays.

Dengler Andrew F.,Weiss Rachel,Truong Tiffany,Irvin Susan C., Gadhia Nidhi, Pfizer,Georgaros Camille,Taylor Jessica-Ann,Paccaly Anne,Sumner Giane,Andisik Matthew D.,Torri Albert,Partridge Michael A.

AAPS Journal（2021）

Cited 4|Views21
Key words
clinical impact,drug concentration assay,immunogenicity,monoclonal antibody therapeutic,prior biologic exposure
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