Rationale and Design of the 2 by 2 Factorial Design GnG-trial: a Randomized Phase-Iii Study to Compare Two Schedules of Gemtuzumab Ozogamicin As Adjunct to Intensive Induction Therapy and to Compare Double-Blinded Intensive Postremission Therapy with or Without Glasdegib in Older Patients with Newly Diagnosed AML