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    • 多模态眼前段成像设备的研发及应用

    肖鹏,王耿媛,段铮昱,袁进,骆仲舟

    Eye science（2021）

    Cited 1|Views5
    Abstract
    目的:获取眼表图像的综合信息,建立眼表疾病综合诊断和评估.方法:将超高分辨率光学相干断层成像仪(ultra-high resolution optical coherence tomography,UHR-OCT)与基于裂隙灯生物显微镜的微血管成像系统相结合,开发了一种多模态、非接触式的眼科光学成像平台.结果:UHR-OCT模块在组织中实现轴向分辨率约为2μm.眼表微血管成像模块在最大放大倍率下横向分辨率约为3.5μm.通过集成在裂隙灯显微镜成像光学路径的不同模块,多模态成像平台能够执行实时前段OCT结构成像、结膜微血管成像和传统裂隙灯成像功能.利用自主开发的软件,进一步分析结膜血管网络图像和血流图像,获取血管分形维数、血流速度、血管直径等定量形态学和血流动力学参数.结论:通过在健康受试者和角膜炎患者的在体成像测试,表明多模态眼前段成像设备可为眼科临床应用及人工智能提供结构和功能信息数据.
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    • Pretraining has recently greatly promoted the development of natural language processing (NLP)
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    【要点】：论文开发了一种多模态、非接触式的眼前段光学成像系统，用于获取眼表图像的综合信息，实现眼表疾病的综合诊断和评估。
    

    【方法】：通过将超高分辨率光学相干断层成像仪（UHR-OCT）与基于裂隙灯生物显微镜的微血管成像系统相结合，构建了一种多模态眼科成像平台。
    

    【实验】：实验使用了UHR-OCT和微血管成像模块，在健康受试者和角膜炎患者身上进行了在体成像测试，数据集名称未提及。UHR-OCT模块实现了轴向分辨率约为2μm，微血管成像模块在最大放大倍率下横向分辨率约为3.5μm，系统能够执行实时前段OCT结构成像、结膜微血管成像和传统裂隙灯成像功能，并通过自主开发的软件分析了血管网络图像和血流图像，获取了定量形态学和血流动力学参数。