孕三烯酮联合腹腔镜治疗子宫内膜异位症对生育功能影响
Chinese Remedies & Clinics（2021）
Abstract
目的 探讨孕三烯酮联合腹腔镜治疗子宫内膜异位症对生育功能的影响.方法 选取2015年8月至2018年10月我院收治的子宫内膜异位症患者86例为研究对象,随机分为研究组与对照组.对照组患者单纯进行腹腔镜治疗,研究组患者经腹腔镜治疗结束后应用孕三烯酮.治疗结束后对2组患者进行随访,对比2组患者临床疗效、治疗前后生殖激素水平、术后1年妊娠成功率、复发率及排卵恢复时间,并观察2组患者不良反应.结果 研究组患者的临床总有效率(91％)明显高于对照组(72％);治疗前,2组患者生殖激素水平对比差异无统计学意义(P>0.05),治疗6个月后,2组患者的催乳素(PRL)、雌二醇(E2)、黄体生成素(LH)、卵泡刺激素(FSH)水平均较治疗前明显降低,且研究组患者的PRL、E2、LH、FSH水平显著低于对照组(P<0.05);研究组患者妊娠率显著高于对照组,复发率显著低于对照组,排卵恢复时间较对照组显著缩短(P<0.05);研究组患者不良反应总发生率显著低于对照组(P<0.05).结论 孕三烯酮联合腹腔镜治疗子宫内膜异位症能够有效提高临床疗效,改善患者生殖激素水平,降低不良反应发生,值得临床推广.
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