A Small Molecule–Drug Conjugate (SMDC) Consisting of a Modified Camptothecin Payload Linked to an Αvß3 Binder for the Treatment of Multiple Cancer Types

Hans-Georg Lerchen,Beatrix Stelte-Ludwig,Charlotte Kopitz,Melanie Heroult,Dmitry Zubov,Joerg Willuda,Thomas Schlange,Antje Kahnert,Harvey Wong,Raquel Izumi,Ahmed Hamdy

Cancers（2022）

引用 15|浏览19

关键词

alpha(V)beta(3) integrin,camptothecin payload,neutrophil elastase,small molecule-drug conjugate,SMDC,SN38 derivative,topoisomerase 1,tumor microenvironment,VIP126,VIP236

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