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Unbound Brain-to-Plasma Partition Coefficient, Kp,uu,brain—a Game Changing Parameter for CNS Drug Discovery and Development

Loryan Irena,Reichel Andreas,Feng Bo,Bundgaard Christoffer,Shaffer Christopher,Kalvass Cory,Bednarczyk Dallas,Morrison Denise,Lesuisse Dominique,Hoppe Edmund,Terstappen Georg C.,Fischer Holger,Di Li,Colclough Nicola,Summerfield Scott,Buckley Stephen T.,Maurer Tristan S.,Fridén Markus

Pharmaceutical Research（2022）

引用 51|浏览42
关键词
blood–brain barrier,CNS drug development,drug transport,neuropharmacokinetics,unbound brain-to-plasma partition coefficient,Kp,uu,brain
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