中性粒细胞与高密度脂蛋白胆固醇比值对老年高血压合并心力衰竭患者的预测价值
Chinese Journal of Geriatric Heart Brain and Vessel Diseases（2022）
Abstract
目的 探索中性粒细胞/高密度脂蛋白胆固醇比值(NHR)对老年高血压合并急性左心力衰竭(心衰)患者30 d主要不良心血管事件(MACE)的预测价值.方法 选择首都医科大学宣武医院急诊科收治的老年高血压合并急性左心衰患者162例,根据血清NHR三分位水平分为低水平组(NHR＜3.73),中水平组(3.73≤NHR＜5.86)和高水平组(NHR≥5.86),每组54例,30 d随访时,记录MACE,用Kaplan-Meier生存曲线分析,用多因素Cox回归分析,ROC曲线分析.结果 30 d随访时,低水平组MACE发生率低于中水平组和高水平组(7.41％vs 12.96％和27.78％,P=0.012);Kaplan-Meier生存曲线示,高水平组MACE发生时间早,发生率最高(Plog rank=0.013).多因素Cox回归分析示,NHR是患者30 d发生MACE的独立预测因素(OR=1.185,95％CI:1.044～1.344,P=0.008).ROC曲线分析示,NHR有预测24、48和72 h心衰好转及30 d发生MACE的价值(P＜0.05,P＜0.01).结论 NHR对老年高血压合并急性左心衰患者病情转归及30 d发生MACE有一定的预测价值.
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