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Orgo-Seq Integrates Single-Cell and Bulk Transcriptomic Data to Identify Cell Type Specific-Driver Genes Associated with Autism Spectrum Disorder.

Elaine T. Lim,Yingleong Chan,Pepper Dawes,Xiaoge Guo,Serkan Erdin,Derek J. C. Tai,Songlei Liu,Julia M. Reichert,Mannix J. Burns,Ying Kai Chan,Jessica J. Chiang,Katharina Meyer,Xiaochang Zhang,Christopher A. Walsh,Bruce A. Yankner,Soumya Raychaudhuri,Joel N. Hirschhorn,James F. Gusella,Michael E. Talkowski,George M. Church

Nature Communications（2022）

Cited 15|Views68
Key words
CRISPR-Cas9 genome editing,Data integration,Experimental models of disease,Gene expression profiling,Neural stem cells,Science,Humanities and Social Sciences,multidisciplinary
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