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Design, Synthesis and Biological Evaluation of Quinoline-2-carbonitrile-based Hydroxamic Acids As Dual Tubulin Polymerization and Histone Deacetylases Inhibitors.

Camille Hauguel, Sarah Ducellier,Olivier Provot,Nada Ibrahim,Diana Lamaa, Coline Balcerowiak,Boris Letribot,Megane Nascimento,Vincent Blanchard,Laurie Askenatzis,Helene Levaique,Jerome Bignon,Francesco Baschieri,Cyril Bauvais,Guillaume Bollot,Dolor Renko,Alain Deroussent,Bastien Prost,Marie-Catherine Laisne,Sophie Michallet,Laurence Lafanechere,Sebastien Papot,Guillaume Montagnac,Christine Tran,Mouad Alami,Sebastien Apcher,Abdallah Hamze

European Journal of Medicinal Chemistry（2022）

Cited 17|Views41
Key words
Cancer,Cytotoxicity,Tubulin,HDACi,Multitargeted compounds
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