Random Forest Modelling Demonstrates Microglial and Protein Misfolding Features to Be Key Phenotypic Markers in C9orf72-ALS

Olivia M. Rifai,James Longden,Judi O'Shaughnessy,Michael De Sewell,Judith Pate,Karina McDade,Michael J. D. Daniels,Sharon Abrahams,Siddharthan Chandran,Barry W. McColl,Christopher R. Sibley,Jenna M. Gregory

JOURNAL OF PATHOLOGY（2022）

Cited 9|Views50

Key words

amyotrophic lateral sclerosis,frontotemporal dementia,C9orf72,neuroinflammation,microglia,post-mortem tissue,TDP-43,fused in sarcoma (FUS),machine learning,digital pathology

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