血清CRP/ALB、LDH与血钙联合检测对早期急性胰腺炎的预测价值
wf（2022）
Abstract
目的 探讨血清C反应蛋白与白蛋白(CRP/ALB)比值、乳酸脱氢酶(LDH)与血钙联合检测对早期急性胰腺炎严重程度的预测价值.方法 选取138例2018.07-2021.06期间于安徽医科大学第一附属医院住院治疗的急性胰腺炎患者资料.将患者分为①MAP及MSAP组(n=100),②SAP组(n=38),共两组.通过单因素分析筛选出与早期AP严重程度相关的指标,再通过多因素分析Logistic回归将独立危险因素筛出.对筛选出的独立因素采用受试者工作特征曲线分析其预测效能.结果 ①SAP组中心率、呼吸、CRP、HCT、D-二聚体、PCT、血淀粉酶、血肌酐、AST、总胆红素、LDH、ALB、CRP/ALB比值较MAP+MSAP组显著增高,ALP轻度降低,血钙显著降低,差异具有统计学意义(P＜0.05).②LDH(OR=1.002,95％CI:1.001～1.003)、血钙(OR=0.134,95％CI:0.027～0.676)、CRP/ALB 比值(OR=1.727,95％CI:1.291～2.310)是发生 SAP 的独立危险因素(P＜0.05).③CRP/ALB比值、LDH、血钙联合检测预测早期AP严重程度分层的价值最高.结论 CRP/ALB比值、LDH、血钙三者联合检测对早期AP严重程度分层具有较高的预测价值.
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