双源CT能谱纯化扫描技术在多发性骨髓瘤中的应用
Chinese Computed Medical Imaging(2022)
Abstract
目的:探讨多发性骨髓瘤患者双源能谱纯化全身低剂量CT(WBLDCT)的临床应用价值.方法:126例多发性骨髓瘤患者随机分为3组.A组:管电压Sn100 kV,螺距1.2;B组:管电压100 kV,螺距1.2;C组:管电压Sn150 kV,螺距3.0.比较3组扫描方案的图像质量、辐射剂量和影像品质因子(FOM).结果:除额骨、枕骨、双侧股骨干外,3组间其余部位的CT值差异无统计学意义(P>0.05).除左肱骨头对比度噪声比(CNR)、左髂骨信噪比(SNR)及CNR、左股骨头CNR外,3组间其余部位的CNR、SNR值存在统计学差异(P<0.05).A组有效辐射剂量(ED)比B组降低了85.81%,比C组降低了81.94%.A组FOM高于B组和C组(P<0.01).3组的图像质量评分无统计学差异(P>0.05),2名评分者之间具有较好的一致性(P>0.05).结论:双源能谱纯化WBLDCT扫描技术在保证图像质量的前提下,显著降低了辐射剂量,可作为多发性骨髓瘤骨质破坏灶筛查的一种手段;因大螺距扫描时间短,对于病情较重者,可选择Sn150 kV高电压大螺距扫描方案.
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