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Inhibition of Cleavage of Human Complement Component C5 and the R885H C5 Variant by Two Distinct High Affinity Anti-C5 Nanobodies.

Eva M. Struijf,Karla I. De la O Becerra,Maartje Ruyken,Carla J. C. de Haas,Fleur van Oosterom,Danique Y. Siere, Joanne E. van Keulen,Dani A. C. Heesterbeek,Edward Dolk,Raimond Heukers,Bart W. Bardoel,Piet Gros,Suzan H. M. Rooijakkers

Journal of Biological Chemistry（2023）

引用 1|浏览16
关键词
complement system,innate immunity,nanobody,single-domain antibody (sdAb nanobody),inhibitor,protein structure,structural model,inflammatory diseases
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