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Spatial and temporal transcriptomics of SHH-medulloblastoma with chromothripsis identifies multiple genetic clones that resist to treatment and lead to relapse

Ilia Kats,Hannah Sophia Schreiber,Milena Simovic,Pooja Sant,Jan-Philipp Mallm,Albert Li,Pravin Velmurugan,Sophie Weil,Frauke Devens,Martin Sill,Manfred Jugold,Mahmoud Moustafa,Amir Abdollahi,Frank Winkler,Andrey Korshunov,Stefan M Pfister,Oliver Stegle,Aurélie Ernst

biorxiv（2023）

Cited 0|Views21
Key words
chromothripsis,temporal transcriptomics,multiple genetic clones,shh-medulloblastoma
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