Generalizable Biomarker Prediction from Cancer Pathology Slides with Self-Supervised Deep Learning: A Retrospective Multi-Centric Study.

Jan Moritz Niehues,Philip Quirke,Nicholas P. West,Heike I. Grabsch,Marko van Treeck,Yoni Schirris,Gregory P. Veldhuizen,Gordon G. A. Hutchins,Susan D. Richman,Sebastian Foersch,Titus J. Brinker,Junya Fukuoka,Andrey Bychkov,Wataru Uegami,Daniel Truhn,Hermann Brenner,Alexander Brobeil,Michael Hoffmeister,Jakob Nikolas Kather

CELL REPORTS MEDICINE（2023）

Cited 41|Views95

Key words

artificial intelligence,biomarker,colorectal cancer,computational pathology,oncogenic mutation,multi-input models,attention-based multiple-instance learning,self-supervised learning,attention heatmaps

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