Sensor for Non-Invasive Detection of SARS-CoV-2 at an Early Stage of Infection
Quantum Sensing and Nano Electronics and Photonics XIX(2023)
Abstract
Fast and non-invasive screening test based on electrochemical detection of structural proteins of SARS-CoV-2 was developed. The measurement being the basis of the test is carried out in a standard three-electrode system, in which the working electrode is covered by bioreceptors immobilized on its surface by durable covalent bonding, ensuring specificity of the detection of desired analyte present in the sample. The carried out measurements allowed for detection of given protein of SARS-CoV-2 in standardized buffered samples and in samples containing virus-like particles. The estimated detection limit of the biosensor does not exceed 10^5 copies of the virus per milliliter.
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