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Mesoscale DNA Feature in Antibody-Coding Sequence Facilitates Somatic Hypermutation

Yanyan Wang,Senxin Zhang,Xinrui Yang,Joyce K. Hwang,Chuanzong Zhan,Chaoyang Lian,Chong Wang,Tuantuan Gui,Binbin Wang,Xia Xie,Pengfei Dai,Lu Zhang, Ying Tian, Huizhi Zhang,Chong Han,Yanni Cai,Qian Hao,Xiaofei Ye,Xiaojing Liu,Jiaquan Liu,Zhiwei Cao,Shaohui Huang, Jie Song,Qiang Pan-Hammarstrom,Yaofeng Zhao,Frederick W. Alt,Xiaoqi Zheng,Lin-Tai Da,Leng-Siew Yeap,Fei-Long Meng

CELL（2023）

Cited 16|Views54
Key words
somatic hypermutation,affinity maturation,complementarity-determining region,AID,deaminase
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