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Generation of Host-Directed and Virus-Specific Antivirals Using Targeted Protein Degradation Promoted by Small Molecules and Viral RNA Mimics

Nan Zhao,Jessica Sook Yuin Ho,Fanye Meng,Simin Zheng,Andrew P. Kurland,Lu Tian,Martha Rea-Moreno, Xiangyang Song,Ji-Seon Seo,H. Umit Kaniskan,Aartjan J. W. te Velthuis,Domenico Tortorella,Ya-Wen Chen,Jeffrey R. Johnson,Jian Jin,Ivan Marazzi

Cell Host & Microbe（2023）

Cited 6|Views21
Key words
PROTAC,influenza virus,SARS-CoV-2,CMV,GSPT1,small molecule,oligonucleotide,antiviral therapeutics
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