A Localizing Nanocarrier Formulation Enables Multi-Target Immune Responses to Multivalent Replicating RNA with Limited Systemic Inflammation.

Taishi Kimura,Joseph M. Leal,Adrian Simpson,Nikole L. Warner,Bryan J. Berube,Jacob F. Archer, Stephanie Park, Ryan Kurtz,Troy Hinkley,Katrina Nicholes, Shibbu Sharma,Malcolm S. Duthie,Peter Berglund,Steven G. Reed,Amit P. Khandhar,Jesse H. Erasmus

MOLECULAR THERAPY（2023）

Cited 19|Views29

Key words

replicating RNA,lipid nanoparticles,RNA vaccines,infectious diseases,innate immunity,LION formulation,nanoparticle emulsion,reactogenicity,side-effect,multivalent vaccines

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