Multi-level Functional Genomics Reveals Molecular and Cellular Oncogenicity of Patient-Based 3′ Untranslated Region Mutations

Samantha L. Schuster,Sonali Arora,Cynthia L. Wladyka,Pushpa Itagi,Lukas Corey, Dave Young,Bethany L. Stackhouse,Lori Kollath,Qian V. Wu,Eva Corey,Lawrence D. True,Gavin Ha,Patrick J. Paddison,Andrew C. Hsieh

CELL REPORTS（2023）

Cited 3|Views33

Key words

3' UTR,untranslated region,mRNA stability,mRNA translation,prostate cancer,somatic mutation,massively parallel reporter assay,ZWILCH,IGF1R,CRISPR-Cas9 base editing

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