Spatial Transcriptomic Patterns Underlying Amyloid-Β and Tau Pathology Are Associated with Cognitive Dysfunction in Alzheimer’s Disease

Meichen Yu,Shannon L. Risacher,Kwangsik T. Nho,Qiuting Wen,Adrian L. Oblak,Frederick W. Unverzagt,Liana G. Apostolova,Martin R. Farlow,Jared R. Brosch,David G. Clark,Sophia Wang,Rachael Deardorff,Yu-Chien Wu,Sujuan Gao,Olaf Sporns,Andrew J. Saykin

Cell reports（2024）

引用 6|浏览6

关键词

Alzheimer’s disease,amyloid-β,cognitive dysfunction,gene expression,pathology,tau,regional vulnerability,spatial associations,biochemical pathways,gene modules

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