Pausing Pluripotency Via RNA Methylation
Nature Cell Biology（2023）SCI 1区
Chinese Acad Sci
Abstract
Embryonic diapause in development and paused pluripotency in embryonic stem cells result in a state of hypotranscription through mechanisms that remain unclear. A new study dissects the role of METTL3-deposited global m6A RNA methylation in mediating this transcriptional dormancy.
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Key words
Embryology,Embryonic stem cells,Life Sciences,general,Cell Biology,Cancer Research,Developmental Biology,Stem Cells
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