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Systematical Evaluation of the Structure-Cardiotoxicity Relationship of 7-Azaindazole-based PI3K Inhibitors Designed by Bioisosteric Approach.

Tianze Wu, Yi Chen,Chengbin Yang,Mingzhu Lu,Fang Geng,Jianhua Guo,Yan Pi,Yun Ling, Jun Xu,Tong Cai,Lei Lu,Yaming Zhou

CARDIOVASCULAR TOXICOLOGY（2023）

Cited 2|Views16
Key words
Structure-cardiotoxicity relationship,Bioisosteric replacement,Zebrafish,Noxo1b,Oxidative stress
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