AI/ML Combined with Next-Generation Sequencing of VHH Immune Repertoires Enables the Rapid Identification of De Novo Humanized and Sequence-Optimized Single Domain Antibodies: a Prospective Case Study.
FRONTIERS IN MOLECULAR BIOSCIENCES（2023）
Key words
artificial intelligence and machine learning (ML),deep learning,in silico developability,long short-term memory (LSTM),next-generation sequencing (NGS),single domain antibodies (VHH),yeast surface display (YSD),protein engineering
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