Conformation-selective Rather Than Avidity-Based Binding to Tumor Associated Antigen Derived Peptide-Mhc Enables Targeting of WT1-pMHC Low Expressing Cancer Cells by Anti-Wt1-pmhc/cd3 T Cell Engagers
Frontiers in Immunology（2023）
关键词
T cell engager,DuetMab,bispecific,conformation,avidity,TCR mimic,target density
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