Ligand-based Targeting of C-Kit Using Engineered Γδ T Cells As a Strategy for Treating Acute Myeloid Leukemia

Gianna M. Branella,Jasmine Y. Lee,Jennifer Okalova,Kiran K. Parwani,Jordan S. Alexander, Raquel F. Arthuzo,Andrew Fedanov,Bing Yu,David Mccarty,Harrison C. Brown,Shanmuganathan Chandrakasan,Brian G. Petrich,Christopher B. Doering,H. Trent Spencer

FRONTIERS IN IMMUNOLOGY（2023）

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关键词

acute myeloid leukemia (AML),gamma delta (gamma delta) T cells,ligand-based therapeutics,chimeric antigen receptor (CAR),secreted bispecific T cell engager,stem cell factor (SCF),c-kit (CD117)

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