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In-depth Mechanistic Analysis Including High-Throughput RNA Sequencing in the Prediction of Functional and Structural Cardiotoxicants Using Hipsc Cardiomyocytes.

Alicia Rosell-Hidalgo,Christopher Bruhn, Emma Shardlow, Ryan Barton,Stephanie Ryder,Timur Samatov, Alexandra Hackmann, Gerald Ryan Aquino, Micael Fernandes Dos Reis,Vladimir Galatenko,Ruediger Fritsch, Cord Dohrmann,Paul A. Walker

Expert Opinion on Drug Metabolism & Toxicology(2023)

Cited 2|Views15
Key words
Cardiotoxicity,HT-transcriptomics,high-content imaging,CaT,hiPSC-CMs,in vitro,predictive
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