Polymorphs, Particle Size, and a Pandemic: Development of a Scalable Crystallization Process for Molnupiravir, an Antiviral for the Treatment of COVID-19 Rachel Bade , Jameson R. Bothe , Eric Sirota , Andrew P. J. Brunskill , Justin A. Newman , Yongqian Zhang , Melissa Tan , Michelle Zheng , Gilmar Brito , Marc Poirier , Patrick S. Fier , Yingju Xu , Michael D. Ward , Kevin Stone , Ivan H. Lee , Andrew J. Gmitter , Frank Bernardoni , Michael A. Zompa , Hanlin Luo , Sanjaykumar Patel , Tina Masiuk , Jeff Mora , Tong Ni , Grace A. Okoh , James Tarabokija , Jiaying Liu , Michael B. Lowinger , Tariq Mahmood ORGANIC PROCESS RESEARCH & DEVELOPMENT（2023）
关键词
polymorph, particle size, crystallization, API, molnupiravir, covid-19, antiviral
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