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Matrixed CDR Grafting: A Neoclassical Framework for Antibody Humanization and Developability

Pankaj Gupta, Alexander M. Horspool, Goral Trivedi, Gina Moretti,Akshita Datar,Zhong-Fu Huang,Jeffrey Chiecko,Cynthia Hess Kenny,Michael S. Marlow

JOURNAL OF BIOLOGICAL CHEMISTRY（2024）

Cited 0|Views16
Key words
humanization,CDR grafting,developability,germlines,biophysical assessment
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