Towards a Science-Based Testing Strategy to Identify Maternal Thyroid Hormone Imbalance and Neurodevelopmental Effects in the Progeny - Part II: How Can Key Events of Relevant Adverse Outcome Pathways Be Addressed in Toxicological Assessments?

Sue Marty,Manon Beekhuijzen,Alex Charlton,Nina Hallmark,Bethany R. Hannas,Sylvia Jacobi,Stephanie Melching-Kollmuss,Ursula G. Sauer,Larry P. Sheets,Volker Strauss,Daniel Urbisch,Philip A. Botham,Bennard van Ravenzwaay

Critical reviews in toxicology（2021）

引用 14|浏览2

关键词

Adverse outcome pathway (AOP),thyroid hormone imbalance,developmental neurotoxicity (DNT),mode-of-action (MoA),molecular initiating event (MIE),uridine diphosphate glucuronyltransferase (UGT),deiodinase (DIO),thyroid peroxidase (TPO),sodium-iodide symporter (NIS)

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