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Breakage Fusion Bridge Cycles Drive High Oncogene Copy Number, but Not Intratumoral Genetic Heterogeneity or Rapid Cancer Genome Change

Siavash Raeisi Dehkordi,Ivy Tsz-Lo Wong,Jing Ni,Jens Luebeck, Kaiyuan Zhu,Gino Prasad, Lena Krockenberger,Guanghui Xu, Biswanath Chowdhury,Utkrisht Rajkumar, Ann Caplin,Daniel Muliaditan,Ceyda Coruh,Qiushi Jin,Kristen Turner, Shu Xian Teo,Andy Wing Chun Pang,Ludmil B Alexandrov,Christelle En Lin Chua,Frank B Furnari,Thomas G Paulson,Julie A Law,Howard Y Chang,Feng Yue,Ramanuj DasGupta,Jean Zhao,Paul S Mischel,Vineet Bafna

bioRxiv the preprint server for biology（2023）

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Key words
Intratumor Heterogeneity
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