Benchmarking and Building DNA Binding Affinity Models Using Allele-Specific and Allele-Agnostic Transcription Factor Binding Data

Xiaoting Li,Lucas A. N. Melo,Harmen J. Bussemaker

GENOME BIOLOGY（2024）

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关键词

Gene expression regulation,Non-coding variants,Transcription factors,Allele-specific binding,ChIP-seq,ChIP-exo,CUT&Tag,CTCF,EBF1,PU.1/SPI1,Motif discovery,Biophysically interpretable machine learning,Statistical modeling

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