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Large-scale Validation of Skin Prion Seeding Activity As a Biomarker for Diagnosis of Prion Diseases

Weiguanliu Zhang,Christina D. Orrú,Aaron Foutz,Mingxuan Ding,Jue Yuan,Syed Zahid Ali Shah,Jing Zhang,Keisi Kotobelli,Maria Gerasimenko,Tricia Gilliland, Wei Chen, Michelle Tang,Mark Cohen,Jiri Safar,Bin Xu,Dao-Jun Hong,Li Cui,Andrew G. Hughson,Lawrence B. Schonberger,Curtis Tatsuoka,Shu G. Chen,Justin J. Greenlee, Zerui Wang,Brian S. Appleby,Byron Caughey,Wen-Quan Zou

Acta neuropathologica（2024）

Cited 5|Views61
Key words
Biomarker,Prion,Skin,Real-time quaking-induced conversion (RT-QuIC),Protein misfolding cyclic amplification (PMCA),Seeding activity
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