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CD8+ T Cell Metabolic Flexibility Elicited by CD28-ARS2 Axis-Driven Alternative Splicing of PKM Supports Antitumor Immunity

G. Aaron Holling,Colin A. Chavel, Anand P. Sharda, Mackenzie M. Lieberman,Caitlin M. James,Shivana M. Lightman, Jason H. Tong,Guanxi Qiao,Tiffany R. Emmons,Thejaswini Giridharan,Shengqi Hou,Andrew M. Intlekofer,Richard M. Higashi,Teresa W. M. Fan,Andrew N. Lane,Kevin H. Eng,Brahm H. Segal,Elizabeth A. Repasky,Kelvin P. Lee,Scott H. Olejniczak

Cellular and Molecular Immunology（2024）

Cited 3|Views38
Key words
Immunometabolism,mRNA splicing,CD8 T cells,ARS2,PKM2
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