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Wnt Dose Escalation During the Exit from Pluripotency Identifies Tranilast As a Regulator of Cardiac Mesoderm

Zhixuan Wu,Sophie Shen,Dalia Mizikovsky,Yuanzhao Cao,Marina Naval-Sanchez,Siew Zhuan Tan,Yanina D. Alvarez,Yuliangzi Sun,Xiaoli Chen,Qiongyi Zhao,Daniel Kim,Pengyi Yang,Timothy A. Hill,Alun Jones,David P. Fairlie,Alice Pebay,Alex W. Hewitt,Patrick P. L. Tam,Melanie D. White,Christian M. Nefzger,Nathan J. Palpant

DEVELOPMENTAL CELL（2024）

Cited 2|Views44
Key words
iPSC,differentiation,Wnt signaling,pluripotency,scRNA-seq,multiple regression,tranilast,Connectivity Map
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