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A targetable PREX2/RAC1/PI3Kβ signalling axis confers resistance to clinically relevant therapeutic approaches in melanoma

Catriona A. Ford, Dana Koludrovic,Patricia P. Centeno,Mona Foth,Elpida Tsonou,Nikola Vlahov,Nathalie Sphyris,Kathryn Gilroy,Courtney Bull,Colin Nixon,Bryan Serrels,Alison F. Munro,John C. Dawson,Neil O. Carragher,Valeria Pavet,David C. Hornigold,Philip D. Dunne,Julian Downward,Heidi C. E. Welch,Simon T. Barry,Owen J. Sansom,Andrew D. Campbell

biorxiv（2024）

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