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Structure-Based Optimization of Selective and Brain Penetrant CK1δ Inhibitors for the Treatment of Circadian Disruptions

Stefan Mccarver, Luke Hanna, Andrew Samant,Aaron A. Thompson,Mark Seierstad,Arjun Saha,Dongpei Wu,Brian Lord,Steven W. Sutton, Vishal Shah,Cynthia M. Milligan,Michelle Wennerholm,Jonathan Shelton,Terry P. Lebold,Brock T. Shireman

ACS Medicinal Chemistry Letters（2024）

引用 0|浏览11
关键词
kinase inhibitor,casein kinase 1 delta,circadianrhythm,mood disorder,autoradiography
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