Artificial and Natural Sweeteners Biased T1R2/T1R3 Taste Receptors Transactivate Glycosylated Receptors on Cancer Cells to Induce Epithelial–Mesenchymal Transition of Metastatic Phenotype

Elizabeth Skapinker, Rashelle Aldbai, Emilyn Aucoin, Elizabeth Clarke,Mira Clark, Daniella Ghokasian, Haley Kombargi, Merlin J. Abraham, Yunfan Li,David A. Bunsick,Leili Baghaie,Myron R. Szewczuk

Nutrients（2024）

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Key words

G protein-coupled receptors,sweeteners,epithelial-mesenchymal transition,pancreatic cancer,glycosylated receptor,migration,tunneling nanotubes

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