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Development and Validation of a Cell-Based Binding Neutralizing Antibody Assay for an Antibody–Drug Conjugate

Weifeng Xu,Nazneen Bano, Olguitza Guzman-Valdes, Jessica Amberman, Elisha Bandlamudi, Pooja Khanna,Rebecca Carmean,Roy Helmy

The AAPS Journal(2024)

Cited 1|Views8
Key words
antibody–drug conjugate (ADC),cell-based killing assay,Fc receptors (FcγRs),immunogenicity testing,Meso Scale Discovery (MSD),neutralizing antibody (NAb)
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