Discovery of Small Molecule Interleukin 17A Inhibitors with Novel Binding Mode and Stoichiometry: Optimization of DNA-Encoded Chemical Library Hits to in Vivo Active Compounds Ashley L. Ramos , Eric R. Goedken , Kristine E. Frank , Maria A. Argiriadi , Sana Bazzaz , Zhiguo Bian , Jesse T. C. Brown , Paolo A. Centrella , Hui-Ju Chen , Jeremy S. Disch , Pamela L. Donner , David B. Duignan , Diana Gikunju , Stephen N. Greszler , Marie-Aude Guie , Sevan Habeshian , Hajnalka E. Hartl , Christopher D. Hein , Charles W. Hutchins , Rachael Jetson , Anthony D. Keefe , Hasan Khan , Huan-Qiu Li , Allison Olszewski , Benjamin J. Ortiz Cardona , Augustine Osuma , Sanjay C. Panchal , Ryan Phelan , Wei Qiu , J. Brad Shotwell , Anurupa Shrestha , Myron Srikumaran , Zhi Su , Chaohong Sun , Anup K. Upadhyay , Michael D. Wood , Haihong Wu , Ruijie Zhang , Ying Zhang , Gang Zhao , Haizhong Zhu , Matthew P. Webster JOURNAL OF MEDICINAL CHEMISTRY（2024）
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