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Synergistic Hyperactivation of Both Mtorc1 and Mtorc2 Underlies the Neural Abnormalities of PTEN-deficient Human Neurons and Cortical Organoids

Navroop K. Dhaliwal, Octavia Yifang Weng,Xiaoxue Dong,Afrin Bhattacharya,Mai Ahmed, Nishimura Haruka,Wendy W. Y. Choi, Aditi Aggarwal,Bryan W. Luikart,Qiang Shu,Xuekun Li,Michael D. Wilson,Jason Moffat,Lu-Yang Wang,Julien Muffat,Yun Li

CELL REPORTS（2024）

引用 2|浏览19
关键词
PTEN,mTOR,brain organoids,neurons,neurodevelopmental disorders,autism,epilepsy
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